77-52-1 ursolic acid manufacturer good supplier fast delivery CAS NO.77-52-1

Ursolic acid is a natural pentacyclic triterpenoid carboxylic acid displaying antitumor activity. It was shown to downregulate the MMP-2 and uPA expression, and also inhibit Na+/K+-ATPase activity (IC50 = 24.7 μM) as well as NF-κB activation in various cancer cell lines. Ursolic acid can induce apoptosis in cancer cells. Ursolic acid also has obvious antioxidant function, so it is widely used as a raw material for medicine and cosmetics.

Metastasis is a major cause of cancer-related mortality in patients with gastric cancer. Ursolic acid, a pentacyclic triterpenoid compound derived from medicinal herbs, has been demonstrated to exert anticancer effects in various cancer cell systems. However, to the best of our knowledge, the inhibitory effect of Ursolic acid on the invasive phenotype of gastric cancer cells has yet to be reported. Therefore, the aim of the present study was to investigate the effect of Ursolic acid on the invasiveness of SNU-484 human gastric cancer cells.

Ursolic acid has medicinally action, both topically and internally. Ursolic acid is used in many cosmetic preparations for its anti-inflammatory, antitumor and antimicrobial properties.
Ursolic acid has antibacterial and antifungal activity. Tests have shown that ursolic acid inhibits the growth of candida albicans and microsporium lenosum.
Ursolic acid has anti-inflammatory properties and is used in ointments to treat burns.
Topical application of ursolic acid inhibited tpa-induced initiation and promotion of tumor growth.

Ursolic Acid 60% is a standardized powder extracted from sage (Salvia officinalis) leaves. Ursolic Acid is a pentacyclic triterpenoid compound that has anti-inflammatory and antimicrobial properties. It enhances hair growth by stimulating the peripheral blood flow in the scalp and helps prevent alopecia and dandruff. Ursolic acid has been used to treat photo-aged skin because it prevents and improves the appearance of wrinkles and age spots by restoring the skin’s collagen bundle structures and its elasticity. This product can be used in skin and hair care formulations and is GMO free and Kosher and Halal certified.